DISEASE MODELS (THERAPEUTIC AREAS)
DISEASE MODELS (THERAPEUTIC AREAS)
DISEASE MODELS (THERAPEUTIC AREAS)
Comprehensive translational in-vivo disease models designed to accelerate
drug discovery, efficacy studies, target validation and IND-enabling studies
across multiple therapeutic areas.
IMMUNOLOGY AND INFLAMMATION
Advanced inflammatory disease models for gastrointestinal, pulmonary,
dermatological and autoimmune disorders.
Intestinal Inflammation
Validated gastrointestinal inflammatory models for IBD and Crohn’s disease research.
- Dextran Sodium Sulphate (DSS)-Induced Colitis Model
- TNBS-Induced Colitis Model
- Indomethacin-Induced Crohn’s Disease Model
Dermal Inflammation
Translational skin inflammation models supporting psoriasis and fibrosis studies.
- Imiquimod-Induced Psoriasis Model
- Oxazolone-Induced Ear/Skin Inflammation Model
- Bleomycin-Induced Skin Fibrosis Model
Lung Inflammation
Respiratory inflammation models supporting COPD, asthma and fibrosis programs.
- LPS-Induced Lung Inflammation Model
- Bleomycin-Induced Lung Inflammation Model
- Silica-Induced Lung Inflammation Model
- Asbestos-Induced Lung Inflammation Model
Inflammatory Arthritis
Clinically relevant models for rheumatoid arthritis and osteoarthritis research.
- Collagen-Induced Arthritis Model
- Adjuvant-Induced Arthritis Model
- MIA-Induced Osteoarthritis Model
PAIN MODELS
Acute and chronic pain models designed to support analgesic drug discovery.
Neuropathic Pain Models
- CCI-Induced Neuropathic Pain Model
- Paclitaxel-Induced Polyneuropathic Pain Model
- STZ-Induced Polyneuropathic Pain Model
Inflammatory Pain Models
- CFA-Induced Pain Model
- λ-Carrageenan-Induced Pain Model
- Formalin-Induced Pain Model
NEUROSCIENCE MODELS
CNS and neurodegenerative disease models supporting translational neuroscience research.
Cognition Models
- Scopolamine-Induced Cognitive Impairment Model
- AlCl3-Induced Dementia Model
Parkinson’s Disease Models
- 6-OHDA-Induced Parkinson’s Model
- Rotenone-Induced Parkinson’s Model
Anxiety and Depression Models
- Anxiety/Depression Induction Model
- Single Housing
- Acute Stress Exposures
- Chronic Stress Exposures
METABOLIC DISEASE MODELS
Translational metabolic disease models for diabetes and obesity research.
Diabetes Models
- Streptozotocin-Induced Diabetes Model
- High Fat Diet-Induced Diabetes Model
KIDNEY DISEASE MODELS
Preclinical renal disease models supporting nephrology drug development.
Renal Injury Models
- Cisplatin-Induced Renal Injury Model
- Adenine-Induced Renal Injury Model
- UUO-Induced Kidney Fibrosis Model
- STZ-Induced Diabetic Nephropathy Model
ONCOLOGY MODELS
Oncology models supporting IND-enabling studies and anticancer drug development.
Xenograft Models
- Human Tumor Xenograft Models
- Nude Mouse Tumor Models
- SCID Mouse Tumor Models
Carcinogen-Induced Models
- DMBA-Induced Tumor Model
- DMH-Induced Cancer Model
- UV-Induced Carcinogenesis Model
WOUND HEALING MODELS
Regenerative medicine and tissue repair models supporting wound therapeutics.
Wound Healing Models
- Burn-Induced Wound Healing Model
- Excision-Induced Wound Healing Model
- Incision-Induced Wound Healing Model
FIBROSIS MODELS
Translational fibrosis models supporting anti-fibrotic drug discovery.
Fibrosis Models
- Bleomycin-Induced Lung Fibrosis Model
- Silica-Induced Lung Fibrosis Model
- CCl4-Induced Liver Fibrosis Model
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