AGROCHEMICALS

AGROCHEMICALS

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AGROCHEMICAL SERVICES

Toxicology & Safety Assessment Studies

Comprehensive agrochemical safety studies conducted in accordance
with OECD guidelines and international regulatory standards.

☣️ Acute Toxicity Studies

  • Acute Oral Toxicity – Rats/Mice (OECD 423 / 420 / 425)
  • OECD 423: Acute Toxic Class Method
  • OECD 420: Fixed Dose Procedure
  • OECD 425: Up and Down Procedure
  • Acute Dermal Toxicity – Rats (OECD 402)
  • Skin Irritation – Rabbit (OECD 404)
  • Eye Irritation – Rabbit (OECD 405)
  • Skin Sensitization – Guinea Pigs (OECD 406)

🧪 Repeated Dose Toxicity Studies

  • 28-Days Repeat Dose Toxicity (OECD 407)
  • 90-Days Repeat Dose Toxicity (OECD 408)
  • 180-Days Repeat Dose Toxicity (OECD 452)
  • Carcinogenicity Studies (OECD 451)
  • Combined Chronic Toxicity / Carcinogenicity (OECD 453)

🧠 Neurotoxicity Studies

  • Neurotoxicity Studies – Rodents (OECD 424)

🧬 Genotoxicity Studies (In-Vivo)

  • In-Vivo Micronucleus Test (OECD 474)
  • Chromosomal Aberration Assay (OECD 475)
  • Local Lymph Node Assay – BrdU ELISA (OECD 429)
  • Alkaline Comet Assay (OECD 489)

🔬 Genotoxicity Studies (In-Vitro)

  • Bacterial Reverse Mutation Test (OECD 471)
  • Mammalian Cell Micronucleus Test (OECD 487)
  • Mammalian Chromosome Aberration Test (OECD 473)
  • Mammalian Cell Gene Mutation Test (OECD 476)
  • Mouse Lymphoma Assay (OECD 490)

🧫 Cytotoxicity Assays

  • MTT Assay
  • Lactate Dehydrogenase (LDH) Assay

🌱 In-Vitro Alternatives to Animal Studies

  • Bovine Corneal Opacity and Permeability Test (BCOP) (OECD 437)
  • Isolated Chicken Eye Test (OECD 438)
  • In-Vitro Ocular Irritation Test (OECD 491 / 492)
  • Reconstructed Human Epidermis Test Method (OECD 439)
  • In-Vitro Dermal Absorption (OECD 428)
  • Local Lymph Node Assay BrdU-ELISA (OECD 429)
  • 3T3 NRU Phototoxicity Test (OECD 432)

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